A company has a health care application, a newly joined user has been added to the Application Developer role. When does the user role take effect?

Answer options:

A.The role will be effective immediately
B.For the role to be effective, it might take up to 30 minutes
C.For the role to be effective, it might take up to 1 hour
D.For the role to be effective, it might take up to 2 hours

Answer: B
When you assign roles or remove role assignments, it can take up to 30 minutes for changes to take effect. 
If you are using the Azure portal, Azure PowerShell, or Azure CLI, you can force a refresh of your role assignment changes by signing out and signing in. 
Option A is incorrect because it would be effective immediately only on logout\login 
Option B is CORRECT because please view the reference URL, Active Directory limits section 
Option C is incorrect because please view the reference URL, Active Directory limits section 

Option B is incorrect as an Update cannot be performed. 
Option D is incorrect because Delete cannot be performed. 
References:

https://docs.microsoft.com/en-us/azure/azure-resource-manager/management/lock-resources